xth_2 protein (beta proteobacterium KB13) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

xth_2

[L] COG0708 Exonuclease III. (256 aa)

Predicted Functional Partners:

nth

0.955

xth_1

0.850

dnaN

0.845

KB13_1238

0.806

prlC

0.803

mutY

0.778

polA

0.773

ptsP

0.773

KB13_457

0.622

murI

0.576

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1238	mutY	KB13_1238	KB13_917	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.465
KB13_1238	xth_1	KB13_1238	KB13_428	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	[L] COG0708 Exonuclease III.	0.806
KB13_1238	xth_2	KB13_1238	KB13_292	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	[L] COG0708 Exonuclease III.	0.806
KB13_457	nth	KB13_457	KB13_768	[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.469
KB13_457	polA	KB13_457	KB13_1229	[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.596
KB13_457	xth_1	KB13_457	KB13_428	[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.	[L] COG0708 Exonuclease III.	0.622
KB13_457	xth_2	KB13_457	KB13_292	[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.	[L] COG0708 Exonuclease III.	0.622
dnaN	mutY	KB13_1152	KB13_917	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.815
dnaN	polA	KB13_1152	KB13_1229	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.992
dnaN	xth_1	KB13_1152	KB13_428	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	[L] COG0708 Exonuclease III.	0.814
dnaN	xth_2	KB13_1152	KB13_292	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	[L] COG0708 Exonuclease III.	0.845
murI	xth_2	KB13_340	KB13_292	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	[L] COG0708 Exonuclease III.	0.576
mutY	KB13_1238	KB13_917	KB13_1238	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	0.465
mutY	dnaN	KB13_917	KB13_1152	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	0.815
mutY	nth	KB13_917	KB13_768	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.665
mutY	polA	KB13_917	KB13_1229	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.405
mutY	xth_1	KB13_917	KB13_428	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[L] COG0708 Exonuclease III.	0.778
mutY	xth_2	KB13_917	KB13_292	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[L] COG0708 Exonuclease III.	0.778
nth	KB13_457	KB13_768	KB13_457	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.	0.469
nth	mutY	KB13_768	KB13_917	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.665