Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
KB13_301Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. (444 aa)    
Predicted Functional Partners:
KB13_1159
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 0.998
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
 
 0.991
lpdA
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
    
 0.982
KB13_276
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 0.965
KB13_1253
Stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.909
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
   
 0.896
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.886
KB13_1036
Two component transcriptional regulator, LuxR family; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.884
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.809
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 0.805
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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