STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KB13_331Transcriptional regulator, GntR family; [K] COG1609 Transcriptional regulators. (236 aa)    
Predicted Functional Partners:
sdhC
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
 
     0.819
sdhA
[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
    0.806
sdhB
SdhB succinate dehydrogenase (iron-sulfur subunit) oxidoreductase protein; [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
   0.793
sdhD
[C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
       0.792
maeB
Bifunctional protein: malate dehydrogenase phosphotransacetylase; [C] COG0281 Malic enzyme.
       0.773
KB13_622
[G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
     0.596
KB13_1202
Hypothetical protein.
       0.508
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
       0.477
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.457
KB13_240
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.457
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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