Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_362Hypothetical protein; [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (328 aa)    
Predicted Functional Partners:
KB13_965
Hypothetical protein.
       0.773
KB13_1241
[R] COG0457 FOG: TPR repeat.
 
 0.671
KB13_695
[F] COG0209 Ribonucleotide reductase, alpha subunit.
       0.590
KB13_510
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
    0.583
KB13_816
Hypothetical protein.
       0.572
KB13_393
Carboxymethylenebutenolidase; [Q] COG0412 Dienelactone hydrolase and related enzymes.
       0.564
KB13_422
[R] COG0666 FOG: Ankyrin repeat.
  
  0.560
thiS
[H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
       0.546
apaG
ApaG protein; [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport.
       0.546
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.546
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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