Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ribE[H] COG0307 Riboflavin synthase alpha chain. (189 aa)    
Predicted Functional Partners:
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 0.999
ribF
Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family.
    
 0.932
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
     
  0.710
KB13_605
Conserved hypothetical protein TIGR00250; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.622
pyrB
[E] COG0078 Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.615
KB13_961
Dihydroorotase, multifunctional complex type; [F] COG0044 Dihydroorotase and related cyclic amidohydrolases.
       0.615
lolD
Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
       0.590
KB13_574
Lipoprotein releasing system, transmembrane protein, LolC/E family; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.
       0.570
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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