KB13_375 protein (beta proteobacterium KB13)

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KB13_375

N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. (134 aa)

Predicted Functional Partners:

KB13_585

0.781

KB13_272

0.773

mpl

0.545

mtgA

0.536

mrcA

0.536

KB13_998

0.531

KB13_222

0.526

anmK

0.508

KB13_404

0.506

KB13_811

0.499

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_222	KB13_375	KB13_222	KB13_375	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	0.526
KB13_222	KB13_998	KB13_222	KB13_998	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	Penicillin-binding protein 7; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.	0.612
KB13_222	mpl	KB13_222	KB13_1049	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase.	0.673
KB13_222	mrcA	KB13_222	KB13_778	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	MrcA penicillin-binding 1 (peptidoglycan synthetase) transmembrane protein; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	0.949
KB13_222	mtgA	KB13_222	KB13_1156	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family.	0.882
KB13_272	KB13_375	KB13_272	KB13_375	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	0.773
KB13_272	KB13_404	KB13_272	KB13_404	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Hypothetical protein.	0.506
KB13_272	KB13_585	KB13_272	KB13_585	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Acriflavin resistance protein; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.997
KB13_272	KB13_811	KB13_272	KB13_811	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Conserved hypothetical protein; [S] COG1714 Predicted membrane protein/domain.	0.499
KB13_375	KB13_222	KB13_375	KB13_222	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	0.526
KB13_375	KB13_272	KB13_375	KB13_272	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.773
KB13_375	KB13_404	KB13_375	KB13_404	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Hypothetical protein.	0.506
KB13_375	KB13_585	KB13_375	KB13_585	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Acriflavin resistance protein; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.781
KB13_375	KB13_811	KB13_375	KB13_811	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Conserved hypothetical protein; [S] COG1714 Predicted membrane protein/domain.	0.499
KB13_375	KB13_998	KB13_375	KB13_998	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Penicillin-binding protein 7; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.	0.531
KB13_375	anmK	KB13_375	KB13_779	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.508
KB13_375	mpl	KB13_375	KB13_1049	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase.	0.545
KB13_375	mrcA	KB13_375	KB13_778	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	MrcA penicillin-binding 1 (peptidoglycan synthetase) transmembrane protein; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.	0.536
KB13_375	mtgA	KB13_375	KB13_1156	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family.	0.536
KB13_404	KB13_272	KB13_404	KB13_272	Hypothetical protein.	Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.506