| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_216 | bioB | KB13_216 | KB13_971 | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.799 |
| KB13_216 | bioC | KB13_216 | KB13_209 | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.858 |
| KB13_216 | bioD | KB13_216 | KB13_125 | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.836 |
| KB13_216 | bioF | KB13_216 | KB13_901 | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Aminotransferases class-I; [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.815 |
| KB13_216 | cspR | KB13_216 | KB13_412 | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | SpoU class tRNA/rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.561 |
| KB13_920 | cspR | KB13_920 | KB13_412 | Hypothetical protein. | SpoU class tRNA/rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.458 |
| KB13_920 | trmB | KB13_920 | KB13_350 | Hypothetical protein. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.495 |
| bioB | KB13_216 | KB13_971 | KB13_216 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.799 |
| bioB | bioC | KB13_971 | KB13_209 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.907 |
| bioB | bioD | KB13_971 | KB13_125 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.998 |
| bioB | bioF | KB13_971 | KB13_901 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Aminotransferases class-I; [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.963 |
| bioB | cspR | KB13_971 | KB13_412 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | SpoU class tRNA/rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.632 |
| bioC | KB13_216 | KB13_209 | KB13_216 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.858 |
| bioC | bioB | KB13_209 | KB13_971 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.907 |
| bioC | bioD | KB13_209 | KB13_125 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.916 |
| bioC | bioF | KB13_209 | KB13_901 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Aminotransferases class-I; [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.882 |
| bioC | cspR | KB13_209 | KB13_412 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | SpoU class tRNA/rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.626 |
| bioD | KB13_216 | KB13_125 | KB13_216 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Carboxylesterase BioH, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.836 |
| bioD | bioB | KB13_125 | KB13_971 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.998 |
| bioD | bioC | KB13_125 | KB13_209 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.916 |
