gshB protein (beta proteobacterium KB13) - STRING interaction network

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gshB

[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family. (306 aa)

Predicted Functional Partners:

gshA

0.984

pepA_1

0.823

pepA_2

0.823

argA

0.817

KB13_113

0.810

gltB

0.809

glyA

0.801

lipA

0.773

lipB

0.773

KB13_351

0.773

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_113	gshB	KB13_113	KB13_414	[O] COG0625 Glutathione S-transferase.	[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.	0.810
KB13_351	gshA	KB13_351	KB13_886	Hypothetical protein.	Glutamate--cysteine ligase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.773
KB13_351	gshB	KB13_351	KB13_414	Hypothetical protein.	[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.	0.773
KB13_351	lipA	KB13_351	KB13_1053	Hypothetical protein.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.773
KB13_351	lipB	KB13_351	KB13_1149	Hypothetical protein.	Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.773
argA	gltB	KB13_561	KB13_763	Amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	0.542
argA	glyA	KB13_561	KB13_542	Amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.465
argA	gshB	KB13_561	KB13_414	Amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.	[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.	0.817
gltB	argA	KB13_763	KB13_561	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	Amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.	0.542
gltB	glyA	KB13_763	KB13_542	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.876
gltB	gshA	KB13_763	KB13_886	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	Glutamate--cysteine ligase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.840
gltB	gshB	KB13_763	KB13_414	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.	0.809
gltB	lipA	KB13_763	KB13_1053	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.432
glyA	argA	KB13_542	KB13_561	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.	0.465
glyA	gltB	KB13_542	KB13_763	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	0.876
glyA	gshB	KB13_542	KB13_414	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.	0.801
glyA	pepA_1	KB13_542	KB13_103	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	[E] COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.797
glyA	pepA_2	KB13_542	KB13_654	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.797
gshA	KB13_351	KB13_886	KB13_351	Glutamate--cysteine ligase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Hypothetical protein.	0.773
gshA	gltB	KB13_886	KB13_763	Glutamate--cysteine ligase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.	0.840