| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1198 | KB13_701 | KB13_1198 | KB13_701 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | 0.901 |
| KB13_1198 | ampG | KB13_1198 | KB13_421 | P-protein; [E] COG1605 Chorismate mutase. | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.630 |
| KB13_1198 | metH | KB13_1198 | KB13_806 | P-protein; [E] COG1605 Chorismate mutase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.525 |
| KB13_1198 | trpD | KB13_1198 | KB13_1203 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.915 |
| KB13_1198 | trpE | KB13_1198 | KB13_106 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.893 |
| KB13_701 | KB13_1198 | KB13_701 | KB13_1198 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | P-protein; [E] COG1605 Chorismate mutase. | 0.901 |
| KB13_701 | ampG | KB13_701 | KB13_421 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.589 |
| KB13_701 | hemA | KB13_701 | KB13_1119 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.545 |
| KB13_701 | hemK | KB13_701 | KB13_761 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Protein methyltransferase HemK; [J] COG2813 16S RNA G1207 methylase RsmC. | 0.545 |
| KB13_701 | metW | KB13_701 | KB13_1172 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Methionine biosynthesis protein MetW; [QR] COG0500 SAM-dependent methyltransferases. | 0.545 |
| KB13_701 | metX | KB13_701 | KB13_599 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.545 |
| KB13_701 | prfA | KB13_701 | KB13_434 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.545 |
| KB13_701 | trpD | KB13_701 | KB13_1203 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| KB13_701 | trpE | KB13_701 | KB13_106 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| ampG | KB13_1198 | KB13_421 | KB13_1198 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | P-protein; [E] COG1605 Chorismate mutase. | 0.630 |
| ampG | KB13_701 | KB13_421 | KB13_701 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | 0.589 |
| ampG | hemA | KB13_421 | KB13_1119 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.773 |
| ampG | hemK | KB13_421 | KB13_761 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Protein methyltransferase HemK; [J] COG2813 16S RNA G1207 methylase RsmC. | 0.773 |
| ampG | metH | KB13_421 | KB13_806 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.750 |
| ampG | metW | KB13_421 | KB13_1172 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Methionine biosynthesis protein MetW; [QR] COG0500 SAM-dependent methyltransferases. | 0.794 |