htpG protein (beta proteobacterium KB13) - STRING interaction network

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htpG

Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. (622 aa)

Predicted Functional Partners:

dnaJ

0.992

groL

0.975

dnaK

0.961

hscA

0.956

fkpA

0.928

KB13_55

0.897

KB13_1241

0.864

groS

0.862

ppiB

0.799

ppiA

0.799

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1241	KB13_55	KB13_1241	KB13_55	[R] COG0457 FOG: TPR repeat.	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	0.815
KB13_1241	dnaJ	KB13_1241	KB13_927	[R] COG0457 FOG: TPR repeat.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.871
KB13_1241	dnaK	KB13_1241	KB13_1276	[R] COG0457 FOG: TPR repeat.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.861
KB13_1241	fkpA	KB13_1241	KB13_1231	[R] COG0457 FOG: TPR repeat.	[O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2.	0.555
KB13_1241	groL	KB13_1241	KB13_1300	[R] COG0457 FOG: TPR repeat.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.495
KB13_1241	hscA	KB13_1241	KB13_1195	[R] COG0457 FOG: TPR repeat.	Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.862
KB13_1241	htpG	KB13_1241	KB13_427	[R] COG0457 FOG: TPR repeat.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.864
KB13_1241	ppiA	KB13_1241	KB13_967	[R] COG0457 FOG: TPR repeat.	Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.893
KB13_1241	ppiB	KB13_1241	KB13_570	[R] COG0457 FOG: TPR repeat.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.893
KB13_55	KB13_1241	KB13_55	KB13_1241	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	[R] COG0457 FOG: TPR repeat.	0.815
KB13_55	dnaJ	KB13_55	KB13_927	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.813
KB13_55	dnaK	KB13_55	KB13_1276	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.647
KB13_55	groL	KB13_55	KB13_1300	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.702
KB13_55	hscA	KB13_55	KB13_1195	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.647
KB13_55	htpG	KB13_55	KB13_427	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.897
KB13_55	ppiA	KB13_55	KB13_967	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.721
KB13_55	ppiB	KB13_55	KB13_570	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.721
dnaJ	KB13_1241	KB13_927	KB13_1241	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	[R] COG0457 FOG: TPR repeat.	0.871
dnaJ	KB13_55	KB13_927	KB13_55	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	0.813
dnaJ	dnaK	KB13_927	KB13_1276	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.999