ppx protein (beta proteobacterium KB13) - STRING interaction network

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Score

ppx

[FP] COG0248 Exopolyphosphatase. (531 aa)

Predicted Functional Partners:

spoT

0.831

KB13_1235

0.589

purM

0.414

metG

0.409

guaB

0.407

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1235	ppx	KB13_1235	KB13_450	PvdS; [S] COG2326 Uncharacterized conserved protein.	[FP] COG0248 Exopolyphosphatase.	0.589
guaB	metG	KB13_378	KB13_818	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.638
guaB	ppx	KB13_378	KB13_450	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	[FP] COG0248 Exopolyphosphatase.	0.407
guaB	purM	KB13_378	KB13_1153	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	0.644
guaB	spoT	KB13_378	KB13_401	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.408
metG	guaB	KB13_818	KB13_378	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.638
metG	ppx	KB13_818	KB13_450	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	[FP] COG0248 Exopolyphosphatase.	0.409
metG	purM	KB13_818	KB13_1153	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	0.492
metG	spoT	KB13_818	KB13_401	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.450
ppx	KB13_1235	KB13_450	KB13_1235	[FP] COG0248 Exopolyphosphatase.	PvdS; [S] COG2326 Uncharacterized conserved protein.	0.589
ppx	guaB	KB13_450	KB13_378	[FP] COG0248 Exopolyphosphatase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.407
ppx	metG	KB13_450	KB13_818	[FP] COG0248 Exopolyphosphatase.	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.409
ppx	purM	KB13_450	KB13_1153	[FP] COG0248 Exopolyphosphatase.	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	0.414
ppx	spoT	KB13_450	KB13_401	[FP] COG0248 Exopolyphosphatase.	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.831
purM	guaB	KB13_1153	KB13_378	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.644
purM	metG	KB13_1153	KB13_818	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.492
purM	ppx	KB13_1153	KB13_450	Phosphoribosylformylglycinamidine cyclo-ligase; [O] COG0071 Molecular chaperone (small heat shock protein).	[FP] COG0248 Exopolyphosphatase.	0.414
spoT	guaB	KB13_401	KB13_378	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.408
spoT	metG	KB13_401	KB13_818	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.450
spoT	ppx	KB13_401	KB13_450	Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	[FP] COG0248 Exopolyphosphatase.	0.831