Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_457[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (201 aa)    
Predicted Functional Partners:
KB13_1268
Short chain dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.773
KB13_337
[L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair.
    
 
 0.671
xth_2
[L] COG0708 Exonuclease III.
   
 0.622
xth_1
[L] COG0708 Exonuclease III.
   
 0.622
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.596
KB13_1078
Secretion protein HlyD; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.559
czcA
Cation efflux system protein CzcA; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.559
KB13_978
[MU] COG1538 Outer membrane protein.
       0.559
ada
[L] COG0350 Methylated DNA-protein cysteine methyltransferase.
  
 
 0.517
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 
 0.481
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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