Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
mraWS-adenosyl-methyltransferase MraW; [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; overlaps another CDS with the same product name. (212 aa)    
Predicted Functional Partners:
mraZ
mraZ protein; [S] COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.
  
  
 0.954
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
  
 0.928
KB13_222
Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.
  
 0.910
KB13_1272
S-adenosyl-methyltransferase MraW; [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; overlaps another CDS with the same product name.
 
     0.812
KB13_693
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit; Belongs to the MurCDEF family. MurE subfamily.
  
 0.791
fhs
Formate--tetrahydrofolate ligase; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
 
      0.745
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.706
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.693
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
    0.675
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.674
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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