| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1254 | KB13_573 | KB13_1254 | KB13_573 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [S] COG4704 Uncharacterized protein conserved in bacteria. | 0.773 |
| KB13_1254 | glmS | KB13_1254 | KB13_504 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.768 |
| KB13_1254 | glmU | KB13_1254 | KB13_1056 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.768 |
| KB13_573 | KB13_1254 | KB13_573 | KB13_1254 | [S] COG4704 Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.773 |
| KB13_573 | glmS | KB13_573 | KB13_504 | [S] COG4704 Uncharacterized protein conserved in bacteria. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.768 |
| KB13_573 | glmU | KB13_573 | KB13_1056 | [S] COG4704 Uncharacterized protein conserved in bacteria. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.768 |
| carB | glmS | KB13_840 | KB13_504 | Carbamoyl-phosphate synthase, large subunit; [C] COG1038 Pyruvate carboxylase; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.731 |
| carB | glnA | KB13_840 | KB13_503 | Carbamoyl-phosphate synthase, large subunit; [C] COG1038 Pyruvate carboxylase; Belongs to the CarB family. | [R] COG3968 Uncharacterized protein related to glutamine synthetase. | 0.710 |
| carB | gltB | KB13_840 | KB13_763 | Carbamoyl-phosphate synthase, large subunit; [C] COG1038 Pyruvate carboxylase; Belongs to the CarB family. | Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3. | 0.852 |
| carB | purL | KB13_840 | KB13_320 | Carbamoyl-phosphate synthase, large subunit; [C] COG1038 Pyruvate carboxylase; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.814 |
| glmM | glmS | KB13_849 | KB13_504 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.915 |
| glmM | glmU | KB13_849 | KB13_1056 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.980 |
| glmM | pgi | KB13_849 | KB13_1116 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.625 |
| glmS | KB13_1254 | KB13_504 | KB13_1254 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.768 |
| glmS | KB13_573 | KB13_504 | KB13_573 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | [S] COG4704 Uncharacterized protein conserved in bacteria. | 0.768 |
| glmS | carB | KB13_504 | KB13_840 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, large subunit; [C] COG1038 Pyruvate carboxylase; Belongs to the CarB family. | 0.731 |
| glmS | glmM | KB13_504 | KB13_849 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.915 |
| glmS | glmU | KB13_504 | KB13_1056 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.979 |
| glmS | glnA | KB13_504 | KB13_503 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | [R] COG3968 Uncharacterized protein related to glutamine synthetase. | 0.733 |
| glmS | gltB | KB13_504 | KB13_763 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3. | 0.837 |
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