STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KB13_52Adenosine kinase, putative; [P] COG0471 Di- and tricarboxylate transporters. (308 aa)    
Predicted Functional Partners:
KB13_777
Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase.
   
 
 0.817
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.809
rpe
[G] COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.809
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.796
purB
Adenylosuccinate lyase; [C] COG0114 Fumarase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.787
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; [R] COG1411 Uncharacterized protein related to proFAR isomerase (HisA).
  
    0.771
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.766
KB13_1241
[R] COG0457 FOG: TPR repeat.
  
 0.764
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.758
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.752
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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