KB13_526 protein (beta proteobacterium KB13)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KB13_526

[R] COG0790 FOG: TPR repeat, SEL1 subfamily. (424 aa)

Predicted Functional Partners:

hisS

0.796

KB13_309

0.679

KB13_751

0.679

dnaJ

0.657

KB13_546

0.616

KB13_572

0.588

KB13_983

0.588

KB13_55

0.571

KB13_301

0.538

KB13_1161

0.528

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1161	KB13_526	KB13_1161	KB13_526	Ste24 endopeptidase; [O] COG0501 Zn-dependent protease with chaperone function.	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	0.528
KB13_1161	dnaJ	KB13_1161	KB13_927	Ste24 endopeptidase; [O] COG0501 Zn-dependent protease with chaperone function.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.412
KB13_301	KB13_309	KB13_301	KB13_309	Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	Conserved hypothetical protein.	0.580
KB13_301	KB13_526	KB13_301	KB13_526	Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	0.538
KB13_301	KB13_751	KB13_301	KB13_751	Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	Lipopolysaccharide kinase (Kdo/WaaP) family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.482
KB13_309	KB13_301	KB13_309	KB13_301	Conserved hypothetical protein.	Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	0.580
KB13_309	KB13_526	KB13_309	KB13_526	Conserved hypothetical protein.	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	0.679
KB13_309	KB13_55	KB13_309	KB13_55	Conserved hypothetical protein.	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	0.674
KB13_309	dnaJ	KB13_309	KB13_927	Conserved hypothetical protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.761
KB13_526	KB13_1161	KB13_526	KB13_1161	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Ste24 endopeptidase; [O] COG0501 Zn-dependent protease with chaperone function.	0.528
KB13_526	KB13_301	KB13_526	KB13_301	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Osmolarity sensor protein EnvZ, putative; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	0.538
KB13_526	KB13_309	KB13_526	KB13_309	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Conserved hypothetical protein.	0.679
KB13_526	KB13_546	KB13_526	KB13_546	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	OmpA/MotB; [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.	0.616
KB13_526	KB13_55	KB13_526	KB13_55	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.	0.571
KB13_526	KB13_572	KB13_526	KB13_572	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Sel1 repeat family protein.	0.588
KB13_526	KB13_751	KB13_526	KB13_751	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Lipopolysaccharide kinase (Kdo/WaaP) family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.679
KB13_526	KB13_983	KB13_526	KB13_983	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	[K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.588
KB13_526	dnaJ	KB13_526	KB13_927	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.657
KB13_526	hisS	KB13_526	KB13_1211	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	[J] COG0441 Threonyl-tRNA synthetase.	0.796
KB13_546	KB13_526	KB13_546	KB13_526	OmpA/MotB; [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.	[R] COG0790 FOG: TPR repeat, SEL1 subfamily.	0.616