Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_544[GEPR] COG0477 Permeases of the major facilitator superfamily. (398 aa)    
Predicted Functional Partners:
KB13_330
Nucleotide binding protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.
       0.786
KB13_114
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; [O] COG0450 Peroxiredoxin.
       0.752
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.750
KB13_1198
P-protein; [E] COG1605 Chorismate mutase.
   
 
  0.630
KB13_604
Radical SAM domain protein; [C] COG0731 Fe-S oxidoreductases.
  
     0.624
KB13_1071
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
       0.609
KB13_781
Hypothetical protein; [R] COG0457 FOG: TPR repeat; TPR repeat.
  
     0.566
KB13_394
Molybdopterin binding domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
   
   0.535
fabD
Malonyl CoA-acyl carrier protein transacylase; [Q] COG3321 Polyketide synthase modules and related proteins.
     
 0.535
fabH
3-oxoacyl-(acyl-carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
    
 0.532
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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