node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KB13_975 | KB13_999 | KB13_975 | KB13_999 | Asparate kinase, monofunctional class; [E] COG0263 Glutamate 5-kinase; Belongs to the aspartokinase family. | [E] COG0460 Homoserine dehydrogenase. | 0.952 |
KB13_975 | metH | KB13_975 | KB13_806 | Asparate kinase, monofunctional class; [E] COG0263 Glutamate 5-kinase; Belongs to the aspartokinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.809 |
KB13_975 | metX | KB13_975 | KB13_599 | Asparate kinase, monofunctional class; [E] COG0263 Glutamate 5-kinase; Belongs to the aspartokinase family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.959 |
KB13_98 | metH | KB13_98 | KB13_806 | [E] COG2873 O-acetylhomoserine sulfhydrylase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.893 |
KB13_98 | metX | KB13_98 | KB13_599 | [E] COG2873 O-acetylhomoserine sulfhydrylase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.830 |
KB13_999 | KB13_975 | KB13_999 | KB13_975 | [E] COG0460 Homoserine dehydrogenase. | Asparate kinase, monofunctional class; [E] COG0263 Glutamate 5-kinase; Belongs to the aspartokinase family. | 0.952 |
KB13_999 | metH | KB13_999 | KB13_806 | [E] COG0460 Homoserine dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.846 |
KB13_999 | metX | KB13_999 | KB13_599 | [E] COG0460 Homoserine dehydrogenase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.902 |
ampG | hemA | KB13_421 | KB13_1119 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.773 |
ampG | hemK | KB13_421 | KB13_761 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Protein methyltransferase HemK; [J] COG2813 16S RNA G1207 methylase RsmC. | 0.773 |
ampG | metW | KB13_421 | KB13_1172 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Methionine biosynthesis protein MetW; [QR] COG0500 SAM-dependent methyltransferases. | 0.809 |
ampG | metX | KB13_421 | KB13_599 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.796 |
ampG | prfA | KB13_421 | KB13_434 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.773 |
ampG | trpC | KB13_421 | KB13_880 | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.545 |
hemA | ampG | KB13_1119 | KB13_421 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | AmpG muropeptide MFS transporter; [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.773 |
hemA | hemK | KB13_1119 | KB13_761 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Protein methyltransferase HemK; [J] COG2813 16S RNA G1207 methylase RsmC. | 0.811 |
hemA | metW | KB13_1119 | KB13_1172 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Methionine biosynthesis protein MetW; [QR] COG0500 SAM-dependent methyltransferases. | 0.773 |
hemA | metX | KB13_1119 | KB13_599 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.773 |
hemA | prfA | KB13_1119 | KB13_434 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.819 |
hemA | trpC | KB13_1119 | KB13_880 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.546 |