Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_618[S] COG2960 Uncharacterized protein conserved in bacteria. (77 aa)    
Predicted Functional Partners:
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase.
       0.642
KB13_1144
TonB family C-terminal domain protein; [M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
       0.642
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.642
KB13_396
Sigma E regulatory protein, MucB/RseB, putative; [T] COG3026 Negative regulator of sigma E activity.
  
     0.528
KB13_634
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.526
hldE
Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
     
  0.500
KB13_246
[S] COG4391 Uncharacterized protein conserved in bacteria.
  
     0.485
KB13_1115
[GEPR] COG0477 Permeases of the major facilitator superfamily.
  
     0.478
KB13_1267
[E] COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
       0.442
amt
Ammonium transporter; [P] COG0004 Ammonia permease.
       0.440
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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