Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
typAGTP-binding protein TypA/BipA; [J] COG0480 Translation elongation factors (GTPases). (603 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.709
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.613
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.518
KB13_626
Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
 
  
 0.517
KB13_1015
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
       0.500
KB13_1036
Two component transcriptional regulator, LuxR family; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
       0.500
rpsI
[J] COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
    0.497
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
  
 0.494
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.490
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
      0.487
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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