KB13_644 protein (beta proteobacterium KB13)

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KB13_644

Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. (278 aa)

Predicted Functional Partners:

thiC

0.994

thiS

0.984

KB13_1125

0.940

thiG

0.840

thiL

0.723

KB13_136

0.687

KB13_810

0.623

KB13_353

0.614

KB13_1099

0.533

KB13_516

0.501

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1099	KB13_516	KB13_1099	KB13_516	Hypothetical protein.	[R] COG4989 Predicted oxidoreductase.	0.489
KB13_1099	KB13_644	KB13_1099	KB13_644	Hypothetical protein.	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	0.533
KB13_1125	KB13_136	KB13_1125	KB13_136	[H] COG0352 Thiamine monophosphate synthase.	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	0.814
KB13_1125	KB13_353	KB13_1125	KB13_353	[H] COG0352 Thiamine monophosphate synthase.	Glutamate-1-semialdehyde 2,1-aminomutase; [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases.	0.475
KB13_1125	KB13_644	KB13_1125	KB13_644	[H] COG0352 Thiamine monophosphate synthase.	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	0.940
KB13_1125	thiC	KB13_1125	KB13_1285	[H] COG0352 Thiamine monophosphate synthase.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.951
KB13_1125	thiG	KB13_1125	KB13_838	[H] COG0352 Thiamine monophosphate synthase.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.908
KB13_1125	thiL	KB13_1125	KB13_1208	[H] COG0352 Thiamine monophosphate synthase.	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.	0.717
KB13_1125	thiS	KB13_1125	KB13_1106	[H] COG0352 Thiamine monophosphate synthase.	[H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis.	0.995
KB13_136	KB13_1125	KB13_136	KB13_1125	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	[H] COG0352 Thiamine monophosphate synthase.	0.814
KB13_136	KB13_644	KB13_136	KB13_644	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	0.687
KB13_136	thiC	KB13_136	KB13_1285	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.861
KB13_136	thiG	KB13_136	KB13_838	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.929
KB13_136	thiS	KB13_136	KB13_1106	Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.	[H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis.	0.997
KB13_353	KB13_1125	KB13_353	KB13_1125	Glutamate-1-semialdehyde 2,1-aminomutase; [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases.	[H] COG0352 Thiamine monophosphate synthase.	0.475
KB13_353	KB13_644	KB13_353	KB13_644	Glutamate-1-semialdehyde 2,1-aminomutase; [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases.	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	0.614
KB13_516	KB13_1099	KB13_516	KB13_1099	[R] COG4989 Predicted oxidoreductase.	Hypothetical protein.	0.489
KB13_516	KB13_644	KB13_516	KB13_644	[R] COG4989 Predicted oxidoreductase.	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	0.501
KB13_644	KB13_1099	KB13_644	KB13_1099	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	Hypothetical protein.	0.533
KB13_644	KB13_1125	KB13_644	KB13_1125	Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.	[H] COG0352 Thiamine monophosphate synthase.	0.940