Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glt[E] COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (540 aa)    
Predicted Functional Partners:
KB13_1085
Glutamate synthase, NADH/nadph, small subunit; [O] COG0492 Thioredoxin reductase.
 
 0.996
gltB
Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.
  
 0.984
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.899
lpdA
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
     
 0.858
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.799
oadA
[I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
     
 0.791
KB13_777
Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase.
     
 0.756
KB13_814
Cyclic nucleotide-binding domain protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.
    
 0.629
KB13_1308
Putative polysaccharide polymerase; [M] COG3307 Lipid A core - O-antigen ligase and related enzymes.
       0.594
glnA
[R] COG3968 Uncharacterized protein related to glutamine synthetase.
  
 
 0.580
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.