Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepA_2Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (492 aa)    
Predicted Functional Partners:
pepA_1
[E] COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family.
  
  
 
0.845
gshB
[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
   
 
 0.823
KB13_1110
Hypothetical protein.
  
    0.821
KB13_812
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
    
  0.807
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
  0.797
gshA
Glutamate--cysteine ligase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.797
KB13_360
[R] COG0795 Predicted permeases; overlaps another CDS with the same product name.
       0.622
KB13_948
[R] COG0795 Predicted permeases; overlaps another CDS with the same product name.
       0.621
KB13_278
Deoxyadenosine kinase, putative; [F] COG1428 Deoxynucleoside kinases.
    
  0.597
nagZ
Beta-hexosaminidase; [G] COG1472 Beta-glucosidase-related glycosidases.
    
 0.590
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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