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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrB[R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (308 aa)    
Predicted Functional Partners:
thrC
[E] COG0498 Threonine synthase.
    
 0.908
KB13_1008
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
    0.853
KB13_999
[E] COG0460 Homoserine dehydrogenase.
    
 0.828
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.812
cysE
Serine O-acetyltransferase; [R] COG0110 Acetyltransferase (isoleucine patch superfamily).
     
  0.797
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.797
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.797
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.797
KB13_203
Conserved hypothetical protein TIGR00730; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.
       0.734
metY
Homocysteine synthase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.711
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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