| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1008 | KB13_203 | KB13_1008 | KB13_203 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Conserved hypothetical protein TIGR00730; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. | 0.702 |
| KB13_1008 | thrB | KB13_1008 | KB13_657 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. | 0.853 |
| KB13_203 | KB13_1008 | KB13_203 | KB13_1008 | Conserved hypothetical protein TIGR00730; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.702 |
| KB13_203 | thrB | KB13_203 | KB13_657 | Conserved hypothetical protein TIGR00730; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. | [R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. | 0.734 |
| KB13_999 | ahcY | KB13_999 | KB13_837 | [E] COG0460 Homoserine dehydrogenase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.809 |
| KB13_999 | cysE | KB13_999 | KB13_178 | [E] COG0460 Homoserine dehydrogenase. | Serine O-acetyltransferase; [R] COG0110 Acetyltransferase (isoleucine patch superfamily). | 0.814 |
| KB13_999 | ilvE | KB13_999 | KB13_413 | [E] COG0460 Homoserine dehydrogenase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.839 |
| KB13_999 | metH | KB13_999 | KB13_806 | [E] COG0460 Homoserine dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.927 |
| KB13_999 | metY | KB13_999 | KB13_773 | [E] COG0460 Homoserine dehydrogenase. | Homocysteine synthase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.747 |
| KB13_999 | metZ | KB13_999 | KB13_629 | [E] COG0460 Homoserine dehydrogenase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.879 |
| KB13_999 | thrB | KB13_999 | KB13_657 | [E] COG0460 Homoserine dehydrogenase. | [R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. | 0.828 |
| KB13_999 | thrC | KB13_999 | KB13_112 | [E] COG0460 Homoserine dehydrogenase. | [E] COG0498 Threonine synthase. | 0.995 |
| ahcY | KB13_999 | KB13_837 | KB13_999 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | [E] COG0460 Homoserine dehydrogenase. | 0.809 |
| ahcY | metH | KB13_837 | KB13_806 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.946 |
| ahcY | metY | KB13_837 | KB13_773 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homocysteine synthase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.724 |
| ahcY | metZ | KB13_837 | KB13_629 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.864 |
| ahcY | thrB | KB13_837 | KB13_657 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | [R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. | 0.797 |
| cysE | KB13_999 | KB13_178 | KB13_999 | Serine O-acetyltransferase; [R] COG0110 Acetyltransferase (isoleucine patch superfamily). | [E] COG0460 Homoserine dehydrogenase. | 0.814 |
| cysE | metH | KB13_178 | KB13_806 | Serine O-acetyltransferase; [R] COG0110 Acetyltransferase (isoleucine patch superfamily). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.834 |
| cysE | metZ | KB13_178 | KB13_629 | Serine O-acetyltransferase; [R] COG0110 Acetyltransferase (isoleucine patch superfamily). | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.749 |