STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rumA23S rRNA (uracil-5-)-methyltransferase; [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (437 aa)    
Predicted Functional Partners:
KB13_755
ErfK/YbiS/YcfS/YnhG; [S] COG1376 Uncharacterized protein conserved in bacteria.
 
     0.836
KB13_34
Propable PolB; [L] COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
       0.792
KB13_1205
[EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.
       0.786
KB13_1107
Extracellular solute-binding protein, family 5; [E] COG0747 ABC-type dipeptide transport system, periplasmic component.
       0.778
KB13_718
[EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.
       0.774
dsbB
Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
     0.663
cysM
Cysteine synthase B; [E] COG1171 Threonine dehydratase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
    0.620
spoT
Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     0.465
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.462
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.443
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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