Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntpANudix hydrolase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (145 aa)    
Predicted Functional Partners:
folE2
Conserved hypothetical protein TIGR00294; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.894
KB13_1125
[H] COG0352 Thiamine monophosphate synthase.
  
 
 0.871
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
  0.841
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.837
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
  0.825
KB13_357
Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
   
  0.816
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
     
  0.799
queD
Queuosine biosynthesis protein QueD; [H] COG0720 6-pyruvoyl-tetrahydropterin synthase.
     
  0.797
KB13_626
Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
 0.792
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
     
 0.791
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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