Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfaFLipopolysaccharide heptosyltransferase II; [M] COG0859 ADP-heptose:LPS heptosyltransferase. (334 aa)    
Predicted Functional Partners:
rfaC
Lipopolysaccharide heptosyltransferase I; [M] COG0859 ADP-heptose:LPS heptosyltransferase.
 
0.975
hldE
Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
  
 0.971
KB13_1201
D,D-heptose 1,7-bisphosphate phosphatase; [E] COG0241 Histidinol phosphatase and related phosphatases.
  
 0.966
rfaD
ADP-glyceromanno-heptose 6-epimerase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases.
 
  
 0.934
KB13_952
three-deoxy-D-manno-octulosonic-acid transferase domain protein, putative; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.893
KB13_1260
Glycosyl transferase, group 1; [M] COG0438 Glycosyltransferase.
  
  
  0.882
KB13_1190
Lipopolysaccharide kinase (Kdo/WaaP) family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
  
  0.866
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
    0.777
KB13_680
Putative glycosyl transferase, family 2; [R] COG1216 Predicted glycosyltransferases.
       0.773
KB13_1241
[R] COG0457 FOG: TPR repeat.
    
 0.729
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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