| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1125 | KB13_207 | KB13_1125 | KB13_207 | [H] COG0352 Thiamine monophosphate synthase. | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | 0.581 |
| KB13_1125 | cyaK | KB13_1125 | KB13_363 | [H] COG0352 Thiamine monophosphate synthase. | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | 0.805 |
| KB13_1125 | dapF | KB13_1125 | KB13_202 | [H] COG0352 Thiamine monophosphate synthase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.453 |
| KB13_1125 | metH | KB13_1125 | KB13_806 | [H] COG0352 Thiamine monophosphate synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.895 |
| KB13_1125 | nadE | KB13_1125 | KB13_426 | [H] COG0352 Thiamine monophosphate synthase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.908 |
| KB13_1125 | ribB | KB13_1125 | KB13_1236 | [H] COG0352 Thiamine monophosphate synthase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.891 |
| KB13_1125 | rppH | KB13_1125 | KB13_788 | [H] COG0352 Thiamine monophosphate synthase. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.871 |
| KB13_207 | KB13_1125 | KB13_207 | KB13_1125 | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | [H] COG0352 Thiamine monophosphate synthase. | 0.581 |
| KB13_207 | cyaK | KB13_207 | KB13_363 | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | 0.906 |
| KB13_207 | ribB | KB13_207 | KB13_1236 | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.877 |
| KB13_207 | rppH | KB13_207 | KB13_788 | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.745 |
| KB13_626 | cyaK | KB13_626 | KB13_363 | Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | 0.670 |
| KB13_626 | rnr | KB13_626 | KB13_1248 | Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.715 |
| KB13_626 | rppH | KB13_626 | KB13_788 | Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.804 |
| cyaK | KB13_1125 | KB13_363 | KB13_1125 | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | [H] COG0352 Thiamine monophosphate synthase. | 0.805 |
| cyaK | KB13_207 | KB13_363 | KB13_207 | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. | 0.906 |
| cyaK | KB13_626 | KB13_363 | KB13_626 | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | Dead/deah box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.670 |
| cyaK | ribB | KB13_363 | KB13_1236 | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.806 |
| cyaK | rppH | KB13_363 | KB13_788 | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.799 |
| dapF | KB13_1125 | KB13_202 | KB13_1125 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | [H] COG0352 Thiamine monophosphate synthase. | 0.453 |
