STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXDNA polymerase subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (512 aa)    
Predicted Functional Partners:
KB13_490
[L] COG2812 DNA polymerase III, gamma/tau subunits.
 
 
0.998
dnaN
[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).
   
 0.997
KB13_271
Conserved hypothetical protein; [L] COG1466 DNA polymerase III, delta subunit.
   
 0.997
dnaE
[L] COG0587 DNA polymerase III, alpha subunit.
 
 
 0.997
KB13_1110
Hypothetical protein.
    
 0.996
KB13_1067
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.993
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
 
 0.989
KB13_234
Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.898
rnhA
RNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
  
 0.868
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.832
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.