STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiGThiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (263 aa)    
Predicted Functional Partners:
thiS
[H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
 
 0.994
KB13_129
FAD dependent oxidoreductase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 0.979
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.958
KB13_136
Hypothetical protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; uba/thif-type NAD/fad binding fold.
 
 0.923
KB13_1125
[H] COG0352 Thiamine monophosphate synthase.
 
 
 0.902
KB13_644
Bifunctional thiED protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase.
 
  
 0.818
apaG
ApaG protein; [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport.
       0.792
KB13_942
MltA; [M] COG2821 Membrane-bound lytic murein transglycosylase.
       0.788
KB13_393
Carboxymethylenebutenolidase; [Q] COG0412 Dienelactone hydrolase and related enzymes.
       0.746
KB13_816
Hypothetical protein.
       0.736
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.