STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ntrCNitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (465 aa)    
Predicted Functional Partners:
KB13_410
Nitrogen regulation protein NtrB; [T] COG0642 Signal transduction histidine kinase.
 0.996
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.928
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
   
 0.851
KB13_180
[T] COG0642 Signal transduction histidine kinase.
 
 0.850
KB13_1241
[R] COG0457 FOG: TPR repeat.
  
 0.840
KB13_1253
Stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.821
KB13_1036
Two component transcriptional regulator, LuxR family; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
    
 0.776
glnA
[R] COG3968 Uncharacterized protein related to glutamine synthetase.
  
  
 0.760
phoR
Phosphate regulon sensor protein; [T] COG0642 Signal transduction histidine kinase.
 
 0.709
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
    
 0.691
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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