Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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KB13_856Peptidase M48, Ste24p; [O] COG0501 Zn-dependent protease with chaperone function. (273 aa)    
Predicted Functional Partners:
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.810
kup
Potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
       0.773
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.773
KB13_1241
[R] COG0457 FOG: TPR repeat.
   
 0.766
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
     
  0.765
KB13_393
Carboxymethylenebutenolidase; [Q] COG0412 Dienelactone hydrolase and related enzymes.
 
      0.642
dapD
[E] COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
       0.605
KB13_540
Glutaredoxin family protein; [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.
       0.591
KB13_1282
TonB-dependent siderophore receptor; [H] COG4206 Outer membrane cobalamin receptor protein.
  
     0.588
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.577
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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