STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citE[G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (282 aa)    
Predicted Functional Partners:
KB13_809
MaoC domain protein; [I] COG2030 Acyl dehydratase.
 
 
 0.958
KB13_885
long-chain-fatty-acid--CoA ligase, putative; [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
  0.947
KB13_622
[G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
  0.933
KB13_42
Putative HpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
  0.920
KB13_240
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.839
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.788
prpC
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
    
  0.738
oadA
[I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 
 0.734
prpD
2-methylcitrate dehydratase; [R] COG2079 Uncharacterized protein involved in propionate catabolism.
  
    0.701
maeB
Bifunctional protein: malate dehydrogenase phosphotransacetylase; [C] COG0281 Malic enzyme.
  
 
  0.599
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
Server load: low (8%) [HD]