Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfaDADP-glyceromanno-heptose 6-epimerase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases. (326 aa)    
Predicted Functional Partners:
hldE
Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
 
 0.994
rfaF
Lipopolysaccharide heptosyltransferase II; [M] COG0859 ADP-heptose:LPS heptosyltransferase.
 
  
 0.934
gltB
Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.
    
  0.803
KB13_952
three-deoxy-D-manno-octulosonic-acid transferase domain protein, putative; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
     
  0.797
KB13_680
Putative glycosyl transferase, family 2; [R] COG1216 Predicted glycosyltransferases.
  
 
  0.779
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.773
KB13_1241
[R] COG0457 FOG: TPR repeat.
 
 0.760
KB13_804
CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase; [C] COG0633 Ferredoxin.
  
 
 0.723
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.694
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.685
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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