Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (323 aa)    
Predicted Functional Partners:
moaE
[H] COG0314 Molybdopterin converting factor, large subunit.
 
 0.966
KB13_394
Molybdopterin binding domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.945
KB13_308
Molybdenum cofactor synthesis domain; [H] COG0521 Molybdopterin biosynthesis enzymes.
 
 
 0.917
moaD
[H] COG1977 Molybdopterin converting factor, small subunit.
  
 
 0.848
KB13_1241
[R] COG0457 FOG: TPR repeat.
    
  0.839
KB13_207
[T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
   
  0.823
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.805
KB13_1253
Stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
     
  0.805
cyaK
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
     
  0.805
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.797
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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