mutY protein (beta proteobacterium KB13) - STRING interaction network

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Score

mutY

A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (294 aa)

Predicted Functional Partners:

xth_2

0.899

xth_1

0.899

nth

0.783

KB13_1044

0.738

dnaN

0.600

KB13_1125

0.542

uppP

0.536

KB13_873

0.515

thiC

0.497

KB13_1238

0.471

Your Current Organism:

beta proteobacterium KB13

NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KB13_1044	mutY	KB13_1044	KB13_917	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.738
KB13_1125	KB13_1238	KB13_1125	KB13_1238	[H] COG0352 Thiamine monophosphate synthase.	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	0.456
KB13_1125	mutY	KB13_1125	KB13_917	[H] COG0352 Thiamine monophosphate synthase.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.542
KB13_1125	thiC	KB13_1125	KB13_1285	[H] COG0352 Thiamine monophosphate synthase.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.951
KB13_1238	KB13_1125	KB13_1238	KB13_1125	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	[H] COG0352 Thiamine monophosphate synthase.	0.456
KB13_1238	mutY	KB13_1238	KB13_917	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.471
KB13_1238	xth_1	KB13_1238	KB13_428	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	[L] COG0708 Exonuclease III.	0.790
KB13_1238	xth_2	KB13_1238	KB13_292	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	[L] COG0708 Exonuclease III.	0.790
KB13_873	mutY	KB13_873	KB13_917	Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.515
dnaN	mutY	KB13_1152	KB13_917	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.600
dnaN	xth_1	KB13_1152	KB13_428	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	[L] COG0708 Exonuclease III.	0.915
dnaN	xth_2	KB13_1152	KB13_292	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	[L] COG0708 Exonuclease III.	0.929
mutY	KB13_1044	KB13_917	KB13_1044	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	0.738
mutY	KB13_1125	KB13_917	KB13_1125	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[H] COG0352 Thiamine monophosphate synthase.	0.542
mutY	KB13_1238	KB13_917	KB13_1238	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.	0.471
mutY	KB13_873	KB13_917	KB13_873	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.515
mutY	dnaN	KB13_917	KB13_1152	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).	0.600
mutY	nth	KB13_917	KB13_768	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.783
mutY	thiC	KB13_917	KB13_1285	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.497
mutY	uppP	KB13_917	KB13_980	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Undecaprenol kinase, putative; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.	0.536