Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhAFormate dehydrogenase, alpha subunit; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing. (946 aa)    
Predicted Functional Partners:
hndC
[C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.
 0.997
KB13_1004
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
 0.996
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 
 0.963
KB13_1085
Glutamate synthase, NADH/nadph, small subunit; [O] COG0492 Thioredoxin reductase.
   
 0.957
nuoE
NADH dehydrogenase i, chain e; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 0.954
KB13_804
CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase; [C] COG0633 Ferredoxin.
    
 0.891
nuoF
NADH oxidoreductase (quinone), F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
  
 0.877
lpdA
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
     
 0.871
gltB
Glutamate synthase, large subunit; [E] COG0070 Glutamate synthase domain 3.
     
 0.871
coxB
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
     
 0.869
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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