Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KB13_949ROK family protein; [KG] COG1940 Transcriptional regulator/sugar kinase. (292 aa)    
Predicted Functional Partners:
pgi
[G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.873
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
    
 0.873
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.839
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.830
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.824
algC
[G] COG1109 Phosphomannomutase.
  
 
 0.824
KB13_593
[G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
     
 0.814
eda
[G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
    
 0.803
KB13_35
Aldose 1-epimerase; [G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.
     
  0.797
KB13_1242
Mannose-1-phosphate guanyltransferase, putative; [M] COG1209 dTDP-glucose pyrophosphorylase.
    
  0.707
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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