| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KB13_1198 | KB13_701 | KB13_1198 | KB13_701 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | 0.901 |
| KB13_1198 | aroA | KB13_1198 | KB13_994 | P-protein; [E] COG1605 Chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.984 |
| KB13_1198 | aroB | KB13_1198 | KB13_66 | P-protein; [E] COG1605 Chorismate mutase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.922 |
| KB13_1198 | aroC | KB13_1198 | KB13_252 | P-protein; [E] COG1605 Chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.953 |
| KB13_1198 | aroE | KB13_1198 | KB13_963 | P-protein; [E] COG1605 Chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.919 |
| KB13_1198 | aroK | KB13_1198 | KB13_507 | P-protein; [E] COG1605 Chorismate mutase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.974 |
| KB13_1198 | aroQ | KB13_1198 | KB13_533 | P-protein; [E] COG1605 Chorismate mutase. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.499 |
| KB13_1198 | oadA | KB13_1198 | KB13_124 | P-protein; [E] COG1605 Chorismate mutase. | [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.404 |
| KB13_701 | KB13_1198 | KB13_701 | KB13_1198 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | P-protein; [E] COG1605 Chorismate mutase. | 0.901 |
| KB13_701 | aroB | KB13_701 | KB13_66 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.450 |
| KB13_701 | aroC | KB13_701 | KB13_252 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.862 |
| KB13_701 | aroE | KB13_701 | KB13_963 | Anthranilate synthase component II; [EF] COG0505 Carbamoylphosphate synthase small subunit. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.782 |
| KB13_777 | aroE | KB13_777 | KB13_963 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.791 |
| KB13_777 | oadA | KB13_777 | KB13_124 | Oxidoreductase, FAD-binding; [C] COG0247 Fe-S oxidoreductase. | [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.854 |
| aroA | KB13_1198 | KB13_994 | KB13_1198 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | P-protein; [E] COG1605 Chorismate mutase. | 0.984 |
| aroA | aroB | KB13_994 | KB13_66 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.994 |
| aroA | aroC | KB13_994 | KB13_252 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
| aroA | aroE | KB13_994 | KB13_963 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.966 |
| aroA | aroK | KB13_994 | KB13_507 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.997 |
| aroA | aroQ | KB13_994 | KB13_533 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.682 |
