Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
msbALipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)    
Predicted Functional Partners:
lpxK_2
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
 0.988
KB13_1084
ABC transporter, ATP-binding protein; [G] COG3839 ABC-type sugar transport systems, ATPase components.
 
    
0.902
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; [M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog; Belongs to the KdsB family.
     
 0.796
lpxK_1
tetraacyldisaccharide-1-P 4-kinase; [S] COG2835 Uncharacterized conserved protein; Belongs to the UPF0434 family.
       0.781
KB13_1185
[U] COG0848 Biopolymer transport protein.
       0.773
KB13_1189
MotA/TolQ/ExbB proton channel; [U] COG0811 Biopolymer transport proteins.
       0.773
KB13_1241
[R] COG0457 FOG: TPR repeat.
   
 0.736
lolD
Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
 
   
0.716
KB13_574
Lipoprotein releasing system, transmembrane protein, LolC/E family; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.
     
 0.671
KB13_176
ABC transporter ATP-binding protein; [V] COG1131 ABC-type multidrug transport system, ATPase component.
 
 
 
0.641
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
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