Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KB13_998Penicillin-binding protein 7; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (285 aa)    
Predicted Functional Partners:
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family.
     
 0.651
mrcA
MrcA penicillin-binding 1 (peptidoglycan synthetase) transmembrane protein; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.
     
 0.651
dacB
[M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
     
 0.651
mrdA
Penicillin-binding protein 2; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.
  
 
 0.632
KB13_222
Peptidoglycan synthetase FtsI; [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.
  
 
 0.612
KB13_801
[E] COG0509 Glycine cleavage system H protein (lipoate-binding).
       0.556
KB13_375
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; [V] COG3023 Negative regulator of beta-lactamase expression.
     
 0.531
KB13_361
Ribosomal large subunit pseudouridine synthase F; [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
      0.457
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
   
 0.445
KB13_625
Peptidase M23B; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.421
Your Current Organism:
beta proteobacterium KB13
NCBI taxonomy Id: 314607
Other names: b. proteobacterium KB13
Server load: low (14%) [HD]