STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDQ02065.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (60 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.702
EDQ02190.1
COG3139 Uncharacterized protein conserved in bacteria.
  
     0.641
ThrA
Bifunctional aspartokinase I/homoserine dehydrogenase I; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 
 0.638
EDQ02066.1
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
    
0.625
EDP98880.1
sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...]
  
     0.612
udk
COG0572 Uridine kinase.
   
  0.584
metL
Bifunctional aspartate kinase II/homoserine dehydrogenase II; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.553
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.550
dsbB
Disulfide bond formation protein b; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
     0.543
ThrC
COG0498 Threonine synthase.
 
  
 0.524
Your Current Organism:
Shewanella benthica
NCBI taxonomy Id: 314608
Other names: S. benthica KT99, Shewanella benthica KT99, Shewanella benthica str. KT99, Shewanella benthica strain KT99
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.