node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKM54353.1 | ribC | SERIO_v1c07910 | SERIO_v1c07920 | Spiralin-like protein. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.464 |
AKM54353.1 | truB | SERIO_v1c07910 | SERIO_v1c07930 | Spiralin-like protein. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.464 |
cdsA | ispF | SERIO_v1c08700 | SERIO_v1c02280 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.503 |
cdsA | pyrH | SERIO_v1c08700 | SERIO_v1c08740 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.672 |
cdsA | ribC | SERIO_v1c08700 | SERIO_v1c07920 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.496 |
cdsA | truB | SERIO_v1c08700 | SERIO_v1c07930 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.429 |
cmk | pyrH | SERIO_v1c03660 | SERIO_v1c08740 | Cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.457 |
cmk | ribC | SERIO_v1c03660 | SERIO_v1c07920 | Cytidylate kinase. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.749 |
coaD | dfp | SERIO_v1c02670 | SERIO_v1c07950 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.943 |
coaD | ispF | SERIO_v1c02670 | SERIO_v1c02280 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.442 |
coaD | ribC | SERIO_v1c02670 | SERIO_v1c07920 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.497 |
dfp | coaD | SERIO_v1c07950 | SERIO_v1c02670 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.943 |
dfp | ribC | SERIO_v1c07950 | SERIO_v1c07920 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.471 |
folC | ispF | SERIO_v1c10500 | SERIO_v1c02280 | Folylpolyglutamate synthase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.497 |
folC | ribC | SERIO_v1c10500 | SERIO_v1c07920 | Folylpolyglutamate synthase. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.481 |
ispF | cdsA | SERIO_v1c02280 | SERIO_v1c08700 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.503 |
ispF | coaD | SERIO_v1c02280 | SERIO_v1c02670 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.442 |
ispF | folC | SERIO_v1c02280 | SERIO_v1c10500 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Folylpolyglutamate synthase. | 0.497 |
ispF | ribC | SERIO_v1c02280 | SERIO_v1c07920 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.473 |
mnmA | ribC | SERIO_v1c06920 | SERIO_v1c07920 | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.691 |