Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfbEO-antigen export system ATP-binding protein RfbE. (247 aa)    
Predicted Functional Partners:
rfbA
O-antigen export system permease protein RfbA.
 
 0.999
RF_0543
Two-domain glycosyltransferase; Belongs to the glycosyltransferase 2 family.
 
 
 0.925
trxA
Thioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
 
     0.865
manC
Mannose-1-phosphate guanylyltransferase.
  
  
 0.860
RF_0228
Unknown.
 
  
 0.712
gltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
       0.705
comF
Competence protein F.
   
    0.693
lgtD
Glycosyltransferase.
 
  
 0.618
kpsF
KpsF protein; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.591
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
     
 0.589
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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