STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RF_0271Toxin of toxin-antitoxin system; Containing PIN domain for nucleic acid binding. (141 aa)    
Predicted Functional Partners:
RF_0272
Antitoxin of toxin-antitoxin system Phd; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
  
 0.964
RF_0731
Antitoxin of toxin-antitoxin system Phd; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
  
 0.840
RF_0701
Toxin of toxin-antitoxin system; Containing PIN domain for nucleic acid binding.
  
   
 0.553
RF_1339
Predicted transcriptional regulator; Containing the CopG/Arc/MetJ DNA-binding domain.
  
     0.530
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.523
RF_0274
Unknown.
       0.523
RF_0269
Unknown.
       0.427
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
       0.427
ecoT
Ecotin precursor; Belongs to the protease inhibitor I11 (ecotin) family.
       0.408
RF_1286
Cytotoxic translational repressor of toxin-antitoxin system RelE; COG2026.
  
   
 0.401
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.