Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proPPermeases of the major facilitator superfamily. (397 aa)    
Predicted Functional Partners:
RF_0392
Transposase; Required for the transposition of the insertion element.
       0.569
RF_0597
Alkylated DNA repair protein.
      
 0.540
RF_0137
Site-specific DNA methylase.
      
 0.514
RF_0138
Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.514
RF_0165
Superfamily I DNA and RNA helicase.
   
  
 0.499
spoT5
Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.
      
 0.499
spoT8
Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.
      
 0.499
spoT10
Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.
      
 0.499
RF_0393
Transposase.
       0.425
relB2
DNA-damage-inducible protein J.
      
 0.414
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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