STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nuoL3NADH dehydrogenase I chain N. (510 aa)    
Predicted Functional Partners:
mnhB
Multisubunit Na+/H+ antiporter, MnhB subunit.
 
 
 0.998
nuoL2
NADH dehydrogenase I chain L.
 
 
 0.995
mnhC
Multisubunit Na+/H+ antiporter, MnhC subunit.
 
 
 0.993
mnhE
Multisubunit Na+/H+ antiporter, MnhE subunit.
 
 
 0.990
nuoN2
NADH:ubiquinone oxidoreductase subunit 2 (chain N).
 
  
 0.987
RF_1014
Monovalent cation/proton antiporter, MnhG/PhaG subunit.
 
 
 0.983
nuoL1
NADH dehydrogenase I chain L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
 
 
 0.947
RF_0894
Multisubunit Na+/H+ antiporter, MnhF subunit.
  
 
 0.929
vapC1
Toxin of toxin-antitoxin system VapC; Toxic component of a type II toxin-antitoxin (TA) system. Has ssRNase activity. Upon expression in E.coli inhibits growth in liquid culture; this toxic effect is neutralized by coexpression with cognate antitoxin VapB1. Its RNase activity is partially inhibited in vitro by VapB1 ; Belongs to the PINc/VapC protein family.
       0.780
vapB1
Antitoxin of toxin-antitoxin system VapB; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC1, partially inhibits the RNase activity of VapC1 in vitro.
       0.780
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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