STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vapC1Toxin of toxin-antitoxin system VapC; Toxic component of a type II toxin-antitoxin (TA) system. Has ssRNase activity. Upon expression in E.coli inhibits growth in liquid culture; this toxic effect is neutralized by coexpression with cognate antitoxin VapB1. Its RNase activity is partially inhibited in vitro by VapB1 ; Belongs to the PINc/VapC protein family. (134 aa)    
Predicted Functional Partners:
vapB2
Antitoxin of toxin-antitoxin system VapB; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli or S.cerevisiae neutralizes the effect of cognate toxin VapC2, partially inhibits the RNase activity of VapC2. Belongs to the VapB family.
 
 
 0.979
vapB1
Antitoxin of toxin-antitoxin system VapB; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC1, partially inhibits the RNase activity of VapC1 in vitro.
     
 0.882
nuoL3
NADH dehydrogenase I chain N.
       0.780
nuoL2
NADH dehydrogenase I chain L.
       0.634
ptrB
Protease II.
       0.581
RF_0272
Antitoxin of toxin-antitoxin system Phd; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.486
RF_0702
Antitoxin of toxin-antitoxin system Phd; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.486
RF_0731
Antitoxin of toxin-antitoxin system Phd; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.486
RF_0459
Unknown.
       0.442
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
Server load: high (94%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.