Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RF_0488Predicted metal-dependent hydrolase. (229 aa)    
Predicted Functional Partners:
nlpD1
Membrane proteins related to metalloendopeptidases; Outer membrane antigenic lipoprotein B precursor.
       0.780
RF_0489
Probable antitoxin of toxin-antitoxin stability system.
       0.718
RF_0490
Probable toxin of toxin-antitoxin system.
       0.718
thyX
Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.681
RF_0193
Unknown.
       0.603
lacA
Ribose-5-phosphate isomerase; Belongs to the LacAB/RpiB family.
       0.569
RF_0915
Methylated-DNA--protein-cysteine methyltransferase.
       0.495
dat
Methylated-DNA--protein-cysteine methyltransferase.
       0.495
pheT
Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.478
RF_0485
Unknown.
       0.445
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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