hflC1 protein (Rickettsia felis) - STRING interaction network

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Score

hflC1

Membrane protease subunits; Stomatin/prohibitin homologs. (311 aa)

Predicted Functional Partners:

ftsH

0.880

mpp

0.750

coxB

0.642

tdpX1

0.625

RF_0044

0.580

RF_1031

0.518

pdhB

0.485

polA

0.482

dprA

0.445

aas

0.435

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0044	hflC1	RF_0044	RF_0533	Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.	Membrane protease subunits; Stomatin/prohibitin homologs.	0.580
RF_1031	hflC1	RF_1031	RF_0533	Unknown; Similar to membrane protein implicated in regulation of membrane protease activity.	Membrane protease subunits; Stomatin/prohibitin homologs.	0.518
aas	hflC1	RF_0417	RF_0533	2-acylglycerophosphoethanolamine acyltransferase.	Membrane protease subunits; Stomatin/prohibitin homologs.	0.435
aas	mpp	RF_0417	RF_0338	2-acylglycerophosphoethanolamine acyltransferase.	Mpp; Similar to mitochondrial protease.	0.669
aas	pdhB	RF_0417	RF_1019	2-acylglycerophosphoethanolamine acyltransferase.	Pyruvate dehydrogenase E1 component, beta subunit precursor; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.831
aas	polA	RF_0417	RF_1239	2-acylglycerophosphoethanolamine acyltransferase.	DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.610
coxB	ftsH	RF_0629	RF_0139	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	0.557
coxB	hflC1	RF_0629	RF_0533	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Membrane protease subunits; Stomatin/prohibitin homologs.	0.642
coxB	mpp	RF_0629	RF_0338	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Mpp; Similar to mitochondrial protease.	0.859
coxB	pdhB	RF_0629	RF_1019	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Pyruvate dehydrogenase E1 component, beta subunit precursor; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.556
dprA	hflC1	RF_0531	RF_0533	Putatie DNA processing protein DprA.	Membrane protease subunits; Stomatin/prohibitin homologs.	0.445
dprA	tdpX1	RF_0531	RF_0532	Putatie DNA processing protein DprA.	Thioredoxin peroxidase 1.	0.462
ftsH	coxB	RF_0139	RF_0629	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	0.557
ftsH	hflC1	RF_0139	RF_0533	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Membrane protease subunits; Stomatin/prohibitin homologs.	0.880
ftsH	mpp	RF_0139	RF_0338	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Mpp; Similar to mitochondrial protease.	0.598
ftsH	pdhB	RF_0139	RF_1019	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Pyruvate dehydrogenase E1 component, beta subunit precursor; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.421
ftsH	polA	RF_0139	RF_1239	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.860
hflC1	RF_0044	RF_0533	RF_0044	Membrane protease subunits; Stomatin/prohibitin homologs.	Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.	0.580
hflC1	RF_1031	RF_0533	RF_1031	Membrane protease subunits; Stomatin/prohibitin homologs.	Unknown; Similar to membrane protein implicated in regulation of membrane protease activity.	0.518
hflC1	aas	RF_0533	RF_0417	Membrane protease subunits; Stomatin/prohibitin homologs.	2-acylglycerophosphoethanolamine acyltransferase.	0.435